April 18, 2014

Prefilled syringe sterile plastic packaging

Although the glass as a drug packaging materials has existed for a long time , but it is not the only option. A high-tech plastic and the new design is the accuracy , pharmaceutical compatibility and barrier properties of the pharmaceutical packaging field to create a new standard.Schott forma vitrum is the world 's leading packaging manufacturers in the pharmaceutical industry . The company has developed a new generation of high-tech plastics . TopPac brands include a range of syringes and vials products that combine Schott advantage in the production and design as well as cyclic olefin copolymer from Ticona 's Topas superior performance. In late April of this year , at an international conference on Oberhausen , this new type of polymer and its potential applications to display .The new drug delivery solutions and diagnosticsDr. Klaus Holtzhauer Schott forma vitrum syringe production manager , explained that container made ??of plastic similar to glass for drug delivery and diagnostics provides a novel solution. They are the precision , drug compatibility and barrier properties of the pharmaceutical packaging field to create a new standard. TopPac transparent plastic container is made ??of borosilicate glass as a good alternative to the pharmaceutical packaging products.Glass injectable drugs is considered good packaging material. Nevertheless , in some cases the glass is not the best choice. For example , there is the risk of fragmentation of the emergency drugs . Market demands are constantly changing , the pharmaceutical industry is continually developing new drugs and, therefore, require a new type of packaging. This is a container for the pharmaceutical industry on the proposed newer, plastic packaging design more stringent requirements. Better compatibility , safe handling of toxic products , active ingredients, longer life , and ease of packaging innovation is a new challenge facing the pharmaceutical packaging industry . Schott has been working closely with pharmaceutical manufacturers to jointly develop a new container industry and to meet the needs of users .Dr. Holtzhauer know that injecting drug market is growing rapidly , in part due to the development of vaccines, drugs, and cosmetics heart disease , medical imaging , self-care and emergency medical services and other fields . As a result, security , user-friendly pharmaceutical packaging demand has greatly increased , especially in the syringe can be directly applied .Strengths in different areasTopPac in the following areas have many advantages:* Suitable solvent , for example, water for injections and the protein product formulation and high viscosity.* Meet the direct application of the syringe stringent industry requirements, you can ensure that drugs are not in contact with the environment , but does not react with drugs.* Vials and syringes prepared by the TopPac can be stored for many years in a small size , because this material to water vapor barrier ability is excellent.Syringes models ranging from 1ml ~ 50ml , but within the range of 1ml ~ 10ml of the more obvious advantages . Because of the flexible material is very good , Schott can provide many special properties , such as integrated Luer lock. TopPac product can be applied directly . After the container by injection molding in a clean room technology production , directly in the form of sterile packaging, sterilization and delivered directly to the client's clean room. Complete syringe device includes all the well-known manufacturers of rubber components can provide. Last year , TopPac syringe can be used for emergency treatment was introduced to Europe in heart patients . Specific research began in the late nineties plastic box Otto Schott Research Center Marienborn 's .CGMP production in accordance with the rulesThis product is currently produced mainly conducted in Switzerland Schott . The company is to produce such products established , and has passed the ISO 9001:2000 and ISO13485 ( medical products ) certified. Syringe production in accordance with cGMP regulations , and meet the standard in packaging design Europe, Japan and the U.S. pharmaceutical industry.Holzhauer told us , in order to meet the quality standards of products used directly , they transport from COC polymer to the factory from the moment on the entire production process strictly checked. Transmitted directly to the material of the injection molding apparatus . In the clean room production process, they are all production process parameters for detection and control , including the application of remote control camera on fully automated production lines adjusted to ensure high product quality.TopPac syringe to avoid the cost and time wasting process , such as cleaning and sterilization. The advantage of these costs on the polymer from the Schott developed aseptic production equipment. Since modern production techniques and the corresponding sterile injection molding apparatus , and other conditions of bacterial and particle- forming device is still open after good control . By optimizing the packing syringes and sterilized by radiation protection devices . Pharmaceutical company responsible for drug solution under sterile conditions to loaded into the syringe , the company received from the company Schott polymer to be used directly TopPac a sterile syringe and sent directly to the factory , so no cleaning or sterilization again.Topas COC tech polymer - another materialIf there is no high-performance polymers , the development of innovative applications in the medical field will not now so compelling. For example , the pharmaceutical packaging field is. Packaging must be able to effectively protect drugs meet stringent industry standards and without problems in the drug delivery process, while also cutting costs and customer satisfaction. To meet these demanding requirements , Ticona has developed a special polymer comprising Topas COC.Two different monomersPlastics from Ticona Topas is a high purity polymer COC ( cyclic olefin copolymer ) . Compared with most other common polymers used in packaging , COC polymer clear plastic packaging chain comprises two different monomers . Topas is a basic component of ethylene and norbornene. By varying the ratio of norbornene , materials may be varied to meet the needs of particular applications in a wide range. For example , changes in the physical and chemical properties allows for the storage of pharmaceutical products in Topas plastic packaging . In addition to weight reduction , to improve tear resistance and transparency plastic packaging box comparable with the glass , the barrier properties and excellent chemical stability . Also, plastic trays this material is preferably an inert , low absorption rate , the surface is not a heavy metal ions are not released . Topas sterilization process in the design and also has some flexibility. In addition to the pharmaceutical packaging, other uses of such materials include :* Other pharmaceutical and cosmetic blister pack ;* Diagnostic applications , such as microtiter equipment , micro- testing equipment , micro- pump devices , microfluidic molecular , micro mixers, small and micro- tube structure chips ;* Flexible packaging films ;* Paper / paperboard coating ;* clamshell boxes Optical applications , such as lenses , prisms , sensors , fiber and films ;* High -frequency applications* Color printer toner resin application ( powder ) ;Topas development trajectory* 1950s : The initial study of clamshell packaging cyclic olefin polymerization experiments done ;* 1990 : At the time the project began COC polymer research center called Hoechst AG places vac tray ;* 1993 : Japan 's Mitsui Petrochemical Company began research and development cooperation, continuous production process attempts ;* 1995 : The first production line to achieve semi-commercial ;* 1996 : Built located Ticona Topas new production lines , production development process Hoechst norbornene ;* 1998 : choose to establish production bases in Oberhausen;* 2000 : annual output of 30,000 tons of Topas COC production line put into use ;* 2004 : Today , Topas has been used in more than 50 areas of the world ;Prefilled syringe sterile plastic packagingAlthough the glass as a drug packaging materials has existed for a long time , but it is not the only option. A high-tech plastic and the new design is the accuracy , pharmaceutical compatibility and barrier properties of the pharmaceutical packaging field to create a new standard.Schott forma vitrum is the world 's leading packaging manufacturers in the pharmaceutical industry . The company has developed a new generation of high-tech plastics . TopPac brands include a range of syringes and vials plastic packaging box products that combine Schott advantage in the production and design as well as cyclic olefin copolymer from Ticona 's Topas superior performance. In late April of this year , at an international conference on Oberhausen , this new type of polymer and its potential applications to display .The new drug delivery solutions and diagnosticsDr. Klaus Holtzhauer Schott forma vitrum syringe vac tray production manager , explained that container made ??of plastic similar to glass for drug delivery and diagnostics provides a novel solution. They are the precision , drug compatibility and barrier properties of the pharmaceutical packaging field to create a new standard. TopPac transparent plastic container is made ??of borosilicate glass as a good alternative to the pharmaceutical packaging products.Glass injectable drugs is considered good packaging material. Nevertheless , in some cases the glass is not the best choice. For example , there is the risk of fragmentation of the emergency drugs . Market demands are constantly changing , the pharmaceutical industry is continually developing new drugs and, therefore, require a new type of packaging. This is a container for the pharmaceutical industry on the proposed newer, more packaging design stringent requirements. Better compatibility , safe handling of toxic products , active ingredients, longer life , and ease of packaging innovation is a new challenge facing the pharmaceutical packaging industry . Schott has been working closely with pharmaceutical manufacturers to jointly develop a new container industry and to meet the needs of users .Dr. Holtzhauer know that injecting drug market is growing rapidly , in part due to the development of vaccines, drugs, and cosmetics heart disease , medical imaging , self-care and emergency medical services and other fields . As a result, security , user-friendly pharmaceutical packaging demand has greatly increased , especially in the syringe can be plastic packaging design directly applied .Strengths in different areasTopPac in the following areas have many advantages:* Suitable solvent , for example, water for injections and the protein product formulation and packaging boxes wholesale high viscosity.* Meet the direct application of the syringe stringent industry requirements, you can ensure that drugs are clear plastic box not in contact with the environment , but does not react with drugs.* Vials and syringes prepared by the TopPac can be stored for many years in a small size , because this material to water vapor barrier ability is excellent.Syringes models ranging from 1ml ~ 50ml , but within the range of 1ml ~ 10ml of the more obvious advantages . Because of the flexible material is very good , Schott can provide many special properties , such as integrated Luer lock. TopPac product can be applied directly . After the container by injection molding in a clean room technology production , directly in the form of sterile packaging, sterilization and delivered directly to the client's clean room. Complete syringe device includes all the well-known manufacturers of rubber components can provide. Last year , TopPac syringe can be used for emergency treatment was introduced to Europe in heart patients . Specific research began in the late nineties Otto Schott Research Center Marienborn 's .CGMP production in accordance with clear plastic packaging the rulesThis product is currently produced mainly conducted in Switzerland Schott . The company is to produce such products established , and has passed the ISO 9001:2000 and ISO13485 ( medical products ) certified. Syringe production in accordance with cGMP regulations , and meet the standard in Europe, Japan and the U.S. pharmaceutical industry.Holzhauer told us , in order to meet the quality standards of products used directly , they transport from COC polymer to the factory from the moment on the entire production process strictly checked. Transmitted directly to the material of the injection molding apparatus . In the clean room production process, they are all production process parameters for detection and control , including the application of remote control camera on fully automated production lines adjusted to ensure high product quality.TopPac syringe to avoid the cost and time wasting process , such as cleaning and sterilization. The advantage of these costs on the polymer from the Schott developed aseptic production equipment. Since modern production techniques and the corresponding sterile injection molding apparatus , and other conditions of bacterial and particle- forming device is still open after good control . By optimizing the clam shells for sale packing syringes and sterilized by radiation protection devices . Pharmaceutical company responsible for drug solution under sterile conditions to loaded into the syringe , the company received from the company Schott polymer to be used directly TopPac a sterile syringe and sent directly to the factory , so no cleaning or sterilization again.Topas COC tech polymer - another materialIf there is no high-performance polymers , the development of innovative applications in the medical field will not now so compelling. For example , the pharmaceutical packaging plastic trays field is. Packaging must be able to effectively protect drugs meet stringent industry standards and without problems in the drug delivery process, while also cutting costs and plastic packaging customer satisfaction. To meet these demanding requirements , Ticona has developed a special polymer comprising Topas COC.Two different monomersPlastics from Ticona Topas is a high purity polymer COC ( cyclic olefin copolymer ) . Compared with most other common polymers used in packaging , COC polymer chain comprises two different monomers . Topas is clamshell packaging a basic component of ethylene and norbornene. By varying the ratio of norbornene , materials may be varied to meet the needs of particular applications in a wide range. For example , changes in the physical and chemical properties allows for the storage of pharmaceutical products in Topas . In addition to weight reduction , to improve tear resistance and transparency comparable with the glass , the barrier properties and excellent chemical stability . Also, this material is preferably an inert , low absorption rate , the surface is not blister packs packaging a heavy metal ions are not released . Topas sterilization process clear plastic box packaging in the design and also has some flexibility. In addition to the pharmaceutical plastic packaging box packaging, other uses of such materials include :* Other pharmaceutical and cosmetic blister pack ;* Diagnostic applications , such as microtiter equipment , micro- testing equipment , micro- pump devices , microfluidic molecular , micro mixers, small and micro- tube structure chips ;* Flexible packaging films ;* Paper / paperboard coating ;* Optical applications , such as lenses , prisms , sensors , fiber and films ;* High -frequency applications* Color printer toner resin application ( powder ) ;Topas development trajectory* 1950s : The initial study of cyclic olefin polymerization experiments done ;* 1990 : At the time the project began COC polymer research center called Hoechst AG places ;* 1993 : Japan 's Mitsui Petrochemical Company began research and development cooperation, continuous production process attempts ;* plastic box 1995 : The first production line to achieve semi-commercial ;* 1996 : Built located Ticona Topas new production lines , production development process Hoechst norbornene ;* 1998 : choose to establish production bases in Oberhausen;* 2000 : annual output of 30,000 tons of Topas COC production line put into use ;* 2004 : Today , Topas has been used in more than 50 areas of the world ;

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